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In summary, these findings show that irisin (including exercise-induced irisin secretion) exerts a myocardial protective role through its anti-inflammation activity, antioxidant stress effect, and anti-apoptosis properties, as well as improving mitochondrial function, promoting angiogenesis and fibrotic remodeling

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[200] [203] Monoamine autoreceptors (e.g., D 2 short, presynaptic 2 , and presynaptic 5-HT 1A ) have the opposite effect of TAAR1, and together these receptors provide a regulatory system for monoamines

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PMC 11948232