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& Hiai, H

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A 2025 meta-analysis (a study that pools data from multiple trials to find patterns) confirmed this ranking, with retatrutide showing a mean difference of -16.34 kg vs tirzepatide's -11.82 kg vs placebo (J Endocrine Soc, 2025)

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The Precision Peptide Genetic Test offered by PlexusDx identifies genetic variants in key pathwaysincluding GLP1R, GIPR, FTO, and MC4Rthat influence how your body responds to weight loss therapy

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Delays the effect of fatigue

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They can

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and a loss of coordination (ataxia)

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