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3.3 Oxidative stress and mitochondrial dysfunction EED-induced oxidative stress represents a central mechanism underlying reproductive toxicity, with mitochondrial dysfunction serving as both cause and consequence of excessive reactive oxygen species production

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Studies in rodents have shown that malathion (100400 mg/kg/day) alters lipid metabolism, increasing the plasma levels of cholesterol, TGs and low-density lipoproteins (LDL) [138,139,140]

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doi: 10.1016/S1474-4422(07)70104-7 30 AlpertJEMischoulonDNierenbergAAFavaM