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Studies conducted thus far have been relatively small and focused primarily on animal models or in vitro experiments

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IGF-IR inhibitors resistance The high failure rate of anti-IGF-IR mAb/inhibitor monotherapy or combinational therapy in clinical trials promotes the investigators to inspect the mechanisms underlying resistance to IGF-IR inhibition in cancer and revisit the strategies to target IGF-IR pathway

Barragn JM, Rodrguez RE, Blzquez E: Changes in arterial blood pressure and heart rate induced by glucagon-like peptide-1-(7-36 amide) in rats

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