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Xia, F., Zhong, Y., Li, M., et al

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Indeed, glutamate excitotoxicity contributes to elevated intra-neuronal calcium levels influencing neuronal survival

Recent metanalysis have revealed significant increase in oxidative stress markers such as MDA and a substantial depletion of antioxidants such as catalase, GSH in the blood, and postmortem brain of PD patients compared to healthy controls 25