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concentration (mg per unit) = total mg in vial (mL of bac water 100) on a U-100 insulin syringe (100 units = 1 mL)

The BNF recently (2019) changed its guidance for the frequency of injections of hydroxocobalamin: Every 2 months in patients who have neurological symptoms Every 2 or 3 months when there are no neurological symptoms

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It is helpful in preventing fatigue and may also be useful in some cases of allergies because it reduces histamine release

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