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In vitro permeation and in vivo adsorption testing confirmed that RGD-GHK achieved a high local concentration in the skin layer, initiating peptide effects and facilitating in vivo wound healing, while maintaining excellent biocompatibility

129,136,137,138,139,140 However, clinical translation of saRNAs remains challenging due to the absence of an immune system in xenograft models and the complexity of drug action in the human body

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Pharmacists should be aware of and be able to confidently identify symptoms of chronic liver disease (e.g