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Sleep restriction increases appetite, impairs recovery, and shifts the partitioning of weight lost during a deficit toward lean mass and away from fat

Eur J Clin Pharmacol 71:691697 Christensen MM, Brasch-Andersen C, Green H et al (2011) The pharmacogenetics of metformin and its impact on plasma metformin steady-state levels and glycosylated hemoglobin A1c

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It provides parallel support for the gut ecosystem during a period of transition