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Because both protocols use a before-bed injection on a 5-days-on/2-days-off schedule, they run cleanly in parallel with no scheduling conflict

The reaction products are quantified via spectrophotometric or fluorometric methods

Additionally, lacosamide, an approved drug for treating epilepsy, has also been reported to induce histone hyperacetylation via reductions of HDACs protein expressions, enhancement of histone acetyltransferase or HDAC inhibition by its metabolites [48, 49]

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& Pillai, A