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It would be a mistake to read this article as saying topical GHK-Cu is definitively proven only that it has more, and more directly relevant, human evidence than the injectable route

Topical vs Injectable Tolerability Topical GHK-Cu appears better tolerated than injectable forms, with topical side effects typically limited to mild redness, itching, or irritation at application site and rare copper uglies phenomenon (anecdotal accelerated skin aging appearance due to potential MMP upregulation, not well-studied)

[DOI] [PubMed] [Google Scholar] 87.Pagano C.W., Wu M., Wu L

Boosts Collagen Level- Vitamin C and hyaluronic face serum increase collagen production

Like all medications, azithromycin can cause side effects

Each turned him down