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Indeed, PRL has been identified as an independent predictor of central and peripheral blood pressure and arterial stiffness, being significantly correlated to HeartScore, a composite index able to predict 10-yr cardiovascular mortality, in healthy women during the first decade after menopause onset (105)

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Entacapone is a specific peripheral catechol- O -methyltransferase inhibitor approved by the US FDA in 1999 to treat patients with advanced Parkinsons disease as an adjuvant drug

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