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Concurrently, the expression of HMG-CoA synthasea pivotal ketogenic enzymemay undergo analogous modulation, while HMG-CoA reductase activity (its downstream counterpart) is suppressed, thereby reducing fatty acid conversion to cholesterol

The theoretical rationale is plausible: by facilitating fatty acid transport into the mitochondria, L-carnitine could, in principle, enhance fat oxidation and thereby support weight reduction

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The BCO1 gene is located on chromosome 16q23.2 and is composed of 11 exons that encode a 547 amino acid protein

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