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In this group, tesamorelin significantly increased GH pulse area and basal GH secretion, although changes were of a smaller absolute magnitude than those among the whole group, which included a greater range of BMIs

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Microglia and astrocytes activation following the ischemia leads to the production of cytokines in ischemic brain tissue, and these cytokines and matrix metal proteinases (MMPs) are critical mediators in BBB injury during ischemic stroke

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