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Most people start noticing subtle changes within the first 2 weeks, with more visible skin brightening and improved complexion occurring around weeks 3-4 of consistent treatment

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10.1111/j.1476-5381.2010.01018.x [DOI] [PMC free article] [PubMed] [Google Scholar] 15

It's the same receptor-mediated melanogenesis happening in tissue with higher baseline melanocyte density

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