Long-term effects unknown : While the clinical trials look good, the long-term safety and efficacy of tirzepatide, especially for weight loss, is still being studied
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Contraindications: Contraindicated in patients with medullary thyroid carcinoma or MEN2
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The study included: 67,769 people with type 2 diabetes and 17,604 people with overweight or obesity and cardiovascular disease but without diabetes
