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doi:10.1093/ajcn/nqx082 Reynolds AN, Cummings J, Tannock G, Mann J
Individuals who react strongly to even small hormonal fluctuations may be more sensitive to any potential indirect effects of creatine on DHT, though this remains theoretical
Unlike traditional medications such as disulfiram, naltrexone, and buprenorphine, which primarily target neurotransmitter pathways directly associated with addiction, GLP-1RAs modulate reward mechanisms indirectly through metabolic and neuroendocrine pathways
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In these situations, NICE recommended that GLP-1 RAs are combined with metformin and an SU [41]
The evolution of guidance reflects growing clinical experience and recognition of the importance of individualized risk assessment
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