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While the preclinical safety profile appears favorable (few adverse effects reported in animal studies), this does not guarantee the same in humans, especially with prolonged use

Igncio, Hypothalamus-pituitary-adrenal and gut-brain axes in biological interaction pathway of the depression, Front

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This approach allows them to serve the research community in a responsible fashion

doi: 10.3389/fendo.2021.775233 69 NagaeMUenoyamaYOkamotoSTsuchidaHIkegamiKGotoTet al