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4.2 Mechanism of action of PDEVs 4.2.1 Intercellular communication and signal regulation PDEVs have emerged as a promising candidate for next-generation drug delivery systems, as they can encapsulate and deliver large quantities of bioactive molecules (Zheng et al., 2024

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However, as the drug is unlicensed, these trial doses do not constitute an approved dosing regimen for general use