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[DOI] [PubMed] [Google Scholar] 35.Tseng CW, Tierney EF, Gerzoff RB, et al

When acetylcholine (or bradykinin or adenosine) binds its receptor on the surface of endothelial cells, a signal cascade, coupled to the activation phospholipase C- (PLC), is initiated

As a result, these agents act together to cause additional oxidative damage, creating a never-ending chain reaction (also may be considered a feed-forward loop)

Instead of dying and shrinking away, treated fat cells at the site get bigger