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People with advanced diabetic retinopathy should discuss risks with their doctor, since rapid improvements in blood sugar from any diabetes treatment can temporarily worsen eye disease

Children under the age of 16 cannot be prescribed this medication

The increase is dose-dependent, typically stabilizes over time, and does not escalate with long-term use

10.1016/j.tem.2015.11.009 17 DahlgrenL

A 2014 in vitro study out of China also showed that leucine was able to facilitate insulin signaling and glucose uptake to help keep blood sugar levels in check

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