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Substantial Weight Loss Over 68 Weeks Participants who received the highest dose (12 mg) experienced an average 28.7 % reduction in body weight, equivalent to roughly 71.2 lbs from their starting weights over 68 weeks, far greater than the placebo group, which saw about a 2.1 % reduction

3-5 GLP-1 drugs work by attaching to special spots in the brain called GLP-1 receptors

Other medications cost more on every plan

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Risk of developing each substance use disorder also declined significantly by 18% for alcohol, 14% for cannabis, 20% for cocaine and nicotine, and 25% for opioids

Clinical trials showed average weight loss of 15%17%, roughly double that of previous drugs