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Thyroid hormone replacement is essential for managing hypothyroidism, and semaglutide does not replace this treatment

18 Lete I, Allu J

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2634 The most profound impact will likely be in accelerating and improving production of new medications (e.g., ref (35)), and in generating data that can be used toward this vital aim (e.g., refs (5, 17, 18, and 3639))

Treatment of Otsuka Long Evans Tokushima Fatty (OLETF) rats, an obese animal model of type 2 diabetes, with the PPAR agonist fenofibrate reduced the decline in beta cell mass and prevented the development of diabetes [23]