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High blood pressure Stroke or cerebrovascular accident Arterial thromboembolic events Allergic reactions (rash, itching, breathing difficulty) Fatigue or joint pain Patients with a history of stroke, heart disease, or high blood pressure should discuss these risks with their doctor prior to treatment

This is not a claim that peptide therapy replaces HRT, PCOS management, or standard metabolic care

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doi: 10.1073/pnas.91.17.8014

Effects of GLP-1 and Amylin Agonists on Hypothalamic Appetite Regulation