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In general, long- and prolonged-acting GLP-1 analogs increase heart rates while short-acting GLP-1 analogs do not [30]

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10.1016/j.cub.2014.12.049 7 BoraldiF.BartolomeoA.Di BariC.CocconiA.QuaglinoD

Except for the presence of two AT-hooks possibly involved in DNA binding 16,17 , the C-terminal quarter of the protein is predicted to be mostly disordered and remains poorly characterized 18,19