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EBioMedicine , 55 , 102759

The study was supported by a grant from the European Research Council (grant no

A 2023 randomized controlled trial published in the BMJ (N=410) found that spironolactone 50 to 100 mg/day produced a significantly greater reduction in acne lesion count versus placebo at 24 weeks, with a mean difference of 12.0 fewer inflammatory lesions (95% CI 7.6 to 16.4, P 90% (albumin) | Low

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