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Zhao et al found that 4-week voluntary exercise preconditioning using a running wheel can reduce TBI-induced brain injury and neuronal death in the hippocampus, cortex, and thalamus and attenuate the activation of neuronal apoptosis pathways, resulting in improved recovery of sensorimotor performance in the beam walk task, as well as cognitive/affective functions in the Morris water maze, novel object recognition, and tail-suspension tests

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Lipogenesis occurs in the fat cells and hepatocytes by converting excess acetyl CoA generated by glycolysis into fatty acids, triglycerides, cholesterol, steroids, and bile salts (Desoye and Herrera, 2021)