Decorin is a small leucine-rich proteoglycan that binds collagen fibrils in the extracellular matrix and contributes to the regulation of collagen fibril diameter, organization, and tissue mechanics
Estrogenic effects of several BPA analogs in the developing zebrafish brain
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The core pathological features of IDD include ECM degradation, NP and annulus fibrosus cell death, as well as oxidative stress and inflammatory responses
Mechanism : Improved cavernous blood flow Improved cavernous oxygen concentration Mechanical dilatation of cavernous arteries and/or mechanical stretching of cavernous and tunical tissues