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ALCAR and KET also activated brainstem nuclei (locus coeruleus, diagonal band, and raphe nuclei) which send aminergic projections to cortical areas and spinal dorsal horns that are involved in pain and mood control (Freo et al., 2010

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By week 48 (approximately month 12), the 12mg group had lost 24.2%, with 93% achieving at least 10% total body weight reduction

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