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Reduced Risk of Cardiovascular Events: Semaglutide has been associated with a lower risk of cardiovascular events in patients with type 2 diabetes

Direct head-to-head comparisons in humans remain limited

In: Der Chirurg, 2014, 85: 963-968 Deutsche Adipositas-Gesellschaft et al.: S3-Leitlinie Adipositas - Prvention und Therapie

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The mechanism appears to involve both central nervous system effects (direct brain receptor activation) and peripheral effects (changes in metabolic hormones that communicate with the brain)

Initial results indicate sustained weight loss Of the 45 participants in the REMAIN-1 trials midpoint cohort, 29 underwent resurfacing and 16 received a sham procedure