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Investment Thesis GLP-1s, also known as glucagon-like peptide-1, is a medication used for weight loss and diabetes management

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The absence of a prescribing clinician means there is no safety monitoring, no dose adjustment based on response, and no management plan if complications arise

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Instead, neuronal GLP-1Rs located outside the BBB primarily serve as peripheral targets for gut-derived or pharmacologically administered GLP-1 (Varin et al., 2019

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