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ERN2 and AGR2 are endoplasmic reticulum stress response proteins that manage gene expression of MUC5AC and MUC5B, and AGR2 also acts as a chaperone for mucin proteins to ensure proper folding (Chen et al., 2019

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Afterward, your doctor will likely increase your dose to 7 mg and then possibly to 14 mg, depending on how your blood sugar responds to the treatment