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Active melanocytes are present in the stria vascularis of the cochlea, in the leptomeninges, in the substantia nigra and locus coerulus of the brain, and in the heart, where they play a number of as yet ill-defined roles[13, 18]

Given that the sources and destinations of metabolites are intricately intertwined, it is inevitable that metabolites mediating acyl PTMs in tumor cells will generate potential crosstalk [92]