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In a first series of experiments, GP was determined at several final concentrations of GSH, and successively of NADPH, of GR and of cumene hydroperoxide in the described order

GLP-1 RAs have high glucose-lowering efficacy, but with variation within the drug class

This imbalance could increase GLUT-4, VEGF, and PPAR- activity, leading to the overgrowth of adipose tissue seen in lipedema

Loi, M., Glazunova, O., Fedorova, T., Logrieco, A

doi: 10.26355/eurrev_202008_22649 219 FenerciogluAK

Acute and chronic activation of GLP-1 receptor signaling also reduces systemic and tissue inflammation in mice and humans, through weight lossdependent and independent mechanisms, actions that may contribute to the expanding spectrum of clinical benefits ascribed to GLP-1 medicines