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Amino acid transporter SLC7A11/xCT at the crossroads of regulating redox homeostasis and nutrient dependency of cancer
Glutathione (GSH), the most abundant thiol-containing antioxidant, is fundamental to re-establishing redox homeostasis
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281,282 Liver-specific KO of upstream Hippo kinases, including MST1/2, LATS1/2, and the adaptor proteins SAV1 and MOB1a/b, leads to decreased YAP phosphorylation and increased nuclear translocation
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