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Driven by persistent hyperglycemia, target organ damage in T2D results from cellular stress, overproduction of reactive oxygen species (ROS), advanced glycation end products (AGEs), and protein kinase C (PKC) activation, ultimately leading to the development of microvascular and macrovascular diseases

In Egypt, CAP is a major public health concern, with a high prevalence and large healthcare costs

they directly impact the functional capacity of the immune system

Individuals with chronic diseases, certain blood disorders, or acute infections may not be suitable for this treatment