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Looking here we can see that Retatrutide results are only about 4-5% shy of Sleeve Gastrectomy, an honest-to-god surgical procedure requiring general anesthesia

MHRA Updated Semaglutide Guidance Including NAION Warning (GOV.UK, February 2026) 3

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[19] These licensed treatments offer a far safer, evidence-based alternative to unlicensed investigational compounds

However, everyone's body is different

This means that other metrics may be better indicators of your progress, such as your clothes fitting differently, increased energy, or improved lab markers