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Jamali-Raeufy N, Alizadeh F, Mehrabi Z, Mehrabi S, Goudarzi M (2021) Acetyl-L-carnitine confers neuroprotection against lipopolysaccharide (LPS) -induced neuroinflammation by targeting TLR4/NFB, autophagy, inflammation and oxidative stress

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Phentermine/topiramate (PHEN/TPM) Weight loss trials PHEN/TPM combines an amphetamine analogue with a gamma-aminobutyric acid (GABA) agonist, glutamate antagonist, and carbonic anhydrase inhibitor

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Taken together, notable successes have been obtained in clinical trials when HCC is treated with immunotherapies combined with systemic monotherapy that has been used alone in the past