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Free peptide, acetate-associated material and other described salts may differ analytically, making exact identity important

Analogs targeting arginase and arginine deiminase, the enzymes involved in arginine depletion, have been developed

11 Lower glutathione levels have also been linked to worse outcomes in infections, including HIV and influenza, likely due to impaired immune cell activity and heightened oxidative stress

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"The rodent data is compelling but cannot substitute for proper clinical development" 14