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Anyone considering or taking tirzepatide should know that it works best when combined with regular exercise and a balanced, low calorie diet, said Isaacs

Lee said, "During treatment, if you experience rapid weight loss of more than 1.5 kg per week, persistent loss of appetite or extremely reduced food intake, pale or clay-colored stools, or discomfort or bloating in the upper right abdomen, these could be precursors to gallstones or pancreatitis, so you should consult your doctor immediately." He added, "When losing weight too quickly, the key to preventing gallstones and pancreatitis is to lower the medication dosage and maintain regular meals containing a small but appropriate amount of fat to ensure smooth bile flow."

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