GLP-1 medications carry important warnings and contraindications, including a boxed warning for thyroid C-cell tumors in rodents (contraindicated in patients with personal/family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2)
Marks SJ, Moore NR, Ryley NG, Clark ML, Pointon JJ, Strauss BJ, et al
Plasma MOTS-c rises acutely following high-intensity interval training and correlates with improvements in VO2 max and insulin sensitivity post-exercise [2]
M.Sylvers-DavieK
Not drinking enough water can make symptoms harder to manage
The hairy appearance is due to elongation of keratinized filiform papillae that may show various colors from yellow-brown to black depending on extrinsic factors, ie, tobacco, coffee, tea, food, and intrinsic factors, ie, chromogenic organisms in the normal flora (19)