glp 1 and gip function GLP‐1, the two incretin hormones: Similarities and differences Major physiological roles of GLP-1

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PYY(3-36) predominantly acts through the Y2 receptor (Y2R) in the hypothalamus to suppress appetite and in peripheral tissues (adipose, skeletal muscle, liver) to enhance insulin sensitivity

The appetite-suppressing effect of GLP-1 is mediated by its action in the brain, whereas its glucose-lowering effect is mainly attributed to enhancement of glucose-stimulated insulin secretion [74]

5 GLP-1 Agonists Side Effects Its important to note that taking GLP-1 agonists can cause several unwanted effects depending on how your body responds to the hormone

Ozempic also causes muscle loss

L'effet est plus rapide et agressif, avec plus d'nergie mais aussi plus de risque d'insomnie ou d'irritabilit