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Levels decline with age , which contributes to thinner skin, slower wound healing, and reduced collagen production

A search strategy combining Medical Subject Headings (MeSH) and free-text keywords was used to ensure the inclusion of appropriate studies that explore the gut microbiome and its role in ME/CFS

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Following living conditions, non-spatial factors (like economic, social, political and personal reasons) also attracts attention

Fernndez-Checa, Liver Unit, Hospital Clnic, Centre Esther Koplowitz, Institut dInvestigacions Biomdiques August Pi i Sunyer (IDIBAPS)Centro de Investigacin Biomdica en Red de Enfermedades Hepticas y Digestivas (CIBERehd), Planta Cuarta, C/Rossell 149, Barcelona 08036, Spain e-mail: [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a Section of the journal Frontiers in Pharmacology

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