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Side effects If nausea or reflux made you skip on purpose, that is a conversation to have before restarting

More worrisome, large doses of berberine may cause diarrhea, stomach upset, and nausea

10.1523/JNEUROSCI.0086-08.2008 99 GilpinN

Amphetamines and caffeine are stimulants that increase alertness, improve focus, decrease reaction time, and delay fatigue, allowing for an increased intensity and duration of training

Edibles may pose less respiratory risk than smoking but carry higher overdose and duration-of-action unpredictability

Most users have noticed a loss of at least 15% of their starting weight, with several losing even more