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So, theres concern that trying to increase energy production by using NAD supplements could potentially support the growth of cancer cells

doi:10.1016/S0140-6736(23)01053-X [2] Jastreboff AM, Kaplan LM, Fras JP, et al

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Valine can be degraded into simpler compounds in the body, but in people with a rare genetic condition called maple syrup urine disease, a faulty enzyme interrupts this process and can prove fatal if untreated

Conclusin: Los suplementos que normalmente no rompen el ayuno son los que no aportan caloras, protena, aminocidos, carbohidratos ni grasas