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[14] In dermal fibroblast culture and in rat wound-chamber models, GHK-Cu has been reported to modulate glycosaminoglycan and small-proteoglycan synthesis increasing chondroitin sulphate and dermatan sulphate accumulation, raising decorin mRNA and lowering biglycan mRNA i.e

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The paper proposes, a final infusion rate of 12.5 mg/kg/h for a 32 g overdose, and a final infusion rate of 18.75 mg/kg/h for a 48 g overdose