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Biotinidase deficiency: the enzymatic defect in late-onset multiple carboxylase deficiency

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Patients report reduced cravings, smaller portion sizes, and a general disinterest in food they previously found compelling

25 It is also likely that BPC-157 can inhibit the effect of a calcium ionophore A23187, which is known to stimulate NO release

This is the more sensitive marker for early deficiency

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