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The NIH recommends that adults over fifty years take a daily vitamin B12 supplement, or that they eat foods fortified with vitamin B12

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It discusses the peptide's pleiotropic effects, including its role in tissue injury, inflammatory bowel disease, and central nervous system disorders, while also addressing its safety profile and the lack of human clinical trials

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This resulted in an increase in annual B 12 testing expenditure from $3.0 million to $5.6 million during the same time period

FEBS Lett 589(3):319325