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53 The detrimental effects are more pronounced with longer-chain SFAs, while monounsaturated fatty acids can mitigate these deficits by enhancing -oxidation and ATP production

1 2 Journal of Neuroscience Research

Mitochondria begin relying more on fat oxidation (fat burning), which is metabolically efficient long-term but requires more oxygen and feels subjectively harder in the moment

Long-Term Tolerance Still Matters Side effects should not be dismissed simply because treatment has continued for several months

Some people absorb and store vitamins more efficiently than others, which means they might need injections less frequently