In patients with T2DM, where islet neogenesis and -cell replication are normal, increased apoptosis is the main cause of the decrease in their -cell numbers, so preventing -cell apoptosis may become an effective means of treating T2DM ( GLP-1 has a beneficial effect on -cell function by promoting -cell proliferation and neogenesis and reducing apoptosis (Zheng et al., 2022)
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Therefore, it is generally advised to stop these drugs before surgery
Cuellar SL, Carter BW, Macapinlac HA, Ajani JA, Komaki R, Welsh JW, Lee JH, Swisher SG , Correa AM, Erasmus JJ, Hofstetter WL
[weak evidence] Diverticular disease of the colon: a deficiency of Western civilization [expert review, ungraded] PLoS One 2015: Dietary intervention for overweight and obese adults: Comparison of low carbohydrate and low fat diets
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