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any time of day Bydureon BCise : Simplified auto-injector version Liraglutide# Victoza (T2D) : 0.6 mg daily for 1 week, then 1.2 mg, max 1.8 mg daily Saxenda (obesity) : 0.6 mg daily, increase weekly by 0.6 mg to 3.0 mg daily Subcutaneous injection at any time, with or without food Pre-filled multi-dose pen, no reconstitution Safety Comparison# Bydureon's microsphere formulation causes subcutaneous nodules at injection sites in 10-15% of patients

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Because Wegovy has a very specific dose-escalation schedule (0.25 mg up to 2.4 mg), your doctor will need to determine the appropriate starting point to avoid severe nausea

GAPDH served as an internal control

Locations were documented using handheld GPS units